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Regulating leukocyte adhesion Furthermore, SDC-1 dynamically regulates leukocyte adhesion through chemokine anchoring, offering a dual role in inflammation control [50, 51]

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Important inflammatory factors such as cyclooxygenase 2 (COX-2), tumor necrosis factor (TNF-), and interleukin-6 (IL-6) are downregulated when prostaglandin E2 (PGE2) is inhibited (57)

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